To the Museum from Quarryville, Strasburg, and points east (i.e. from DE by PA 896):

From Quarryville, take US 222 (Beaver Valley Pike) north. You will come to a traffic signal at Penn Grant Road about two miles north of Refton: this is the first traffic light north of Quarryville. Turn left onto Penn Grant road, travel about 3/4 of a mile to Hans Herr Drive, the first road to your right; turn right and follow Hans Herr Drive about 1/2 mile to the Museum on your right.

From Strasburg, take PA 741 west from the square, through the traffic light at the square in Lampeter, to the junction with US 222; turn right onto 222 and follow it about 1/2 mile to the first road to your left: Hans Herr Drive. Turn left onto Hans Herr Drive and follow it about 3/4 of a mile to the Museum on your left.